Long term opiate use safe; One woman’s experience with Savella

There are two great arti­cles from Karen Lee Richards in HealthCentral’s Chronic Pain Con­nec­tion newslet­ter today.

The first, Long-Term Opioid Therapy – What Are the Effects?, brings us the results of Dr. Forest Tennant's ground-breaking study. He evaluated 24 chronic pain patients from 30 to 79 years old who had been using opioids for 10 to 35 years, and "concluded that the significant improvements in quality of life and physical functioning from opioid therapy are so positive they outweigh any negative complications, which can be easily managed."

Almost all of the patients (22 of 24) said their pain had permanently decreased over time. And the vast majority (20 of 24) felt their opioids still provided the same relief as when they started treatment. All of the patients reported one or more functions or activities they can do now that they couldn't do prior to beginning opioid therapy (i.e., get out of bed everyday, take walks, shop or visit friends).

The article details the patients' diagnoses and gives further information, and I encourage you to read the rest of it. While the study was small and obviously needs to be repeated with a larger group, this is marvelous news, and I for one am very grateful for Dr. Tennant's work and the participation of his subjects.

I have to say that I find HealthCentral's sites to be generaly decent, but the Chronic Pain Connection is outstanding. I encourage you to visit and subscribe to the newsletter.

Next, in One Patient’s Expe­ri­ence with Savella for Fibromyal­gia, Richards brings us detailed feed­back from one of her con­tacts, Brenda, who has been tak­ing the new drug for seven weeks. Many of us have heard of Savella, but so few have had an oppor­tu­nity to try it or know any­one who have that this arti­cle is very help­ful in mak­ing a deci­sion as to whether or not to ask our physi­cians for it. After read­ing about Brenda’s advice regard­ing insur­ance expe­ri­ences, deal­ing with side effects, and pos­i­tive results, I for one will be talk­ing to my neu­rol­o­gist about a trial pack.

December 3, 2009  Tags: chronic pain, Forest Tennant, Karen Lee Richards, opiates, Savella  Posted in: Fibromyalgia, Pain, Resources, treatments

6 Responses

  1. Karen Lee Richards - January 19, 2010

    On behalf of Chron­ic­PainCon­nec­tion, I’d like to thank you for your very kind words. It means a lot to know that our site is help­ing to pro­vide use­ful infor­ma­tion and encouragement.

    I also wanted to tell you that I love the title of your blog! So clever – and it projects such a won­der­ful, pos­i­tive atti­tude. I appre­ci­ate your efforts here to edu­cate and sup­port peo­ple with fibromyal­gia. – Karen

  2. pamela smeberg - June 20, 2010

    Thank you so much for bring­ing to light a cred­i­ble study done on patients with chronic pain who have found that there can stil be qual­ity of life in spite of severe chronic pain through long term use of opi­ate ther­apy. I have been on a strong dose of opi­ates for 15 years. Had I not been place on it, I most assuredly would have com­mit­ted sui­cide by now. I have never been sus­pected of being “under the influ­ence” of any sub­stance. I can think and speak clearly and most of all I can live a fairly nor­mal life. Because I have been on opi­ates for 32 out of my 61 years sev­eral pain spe­cial­ists have explained that even if there were alter­na­tive treat­ments to relieve my pain (which is at mul­ti­ple sites and of dif­fer­ing ori­gins) it would be a very dif­fi­cult course requir­ing years of emo­tional upheavals. My brain has been irrev­o­ca­bly changed at the cel­lu­lar level where the opi­ate recep­tors are found and they may never recover their abil­ity to pro­duce endor­phins that are found in the nor­mal brain. I have accepted the inevitabil­ity of not try­ing to fix some­thing that to me is not bro­ken and take my pain meds along with my thy­roid meds, my estro­gen, and my blood pres­sure med. Con­sid­er­ing my lifes­pan may not be much more than 20–25 years, I choose not to go down a path that would require the use of SSRI’s (which may or may not work and would prob­a­bly have to be changed sev­eral times to get the right one); I would also have to face decades of deep depres­sion. many vis­its to a psy­chi­a­trist among other ther­a­pies. Although my con­di­tions are not at all sta­tic (I have recently devel­oped severe mus­cle spasms in my upper and lower back due to bone spurs on the ver­te­brae, I will deal with this addi­tional issues as they occur. Unfor­tu­nately so many doc­tors have made me feel like a drug addict or drug seeker, that it was truly refresh­ing to learn that there are oth­ers out there liv­ing their lives to a full extent thanks to the old­est and most respected pain med­ica­tion on earth.

  3. Gilbert Blaum - December 18, 2010

    I’m a physcian of 40 years doing fam­ily prac­tice (car­ing for the whole body) and for 30 felt ter­ri­ble being unable to treat pts with opi­ates in ade­quate dose because of peer criti­sizm. I began read­ing every arti­cle i could find by Dr Ten­nant. That was 8 years ago and now limit my prac­tice pri­mar­ily to pain con­trol using his pro­to­cols etc. Wow, what a sat­is­fy­ing expe­ri­ence. I can’t count the num­ber of unem­ployed “drug addicts” accord­ing to ER’s and many other MD’s that are back in the work force and being an active and pro­duc­tive human in soci­ety. We all thank you Dr Tennant

  4. Eric Machiavelli - April 2, 2011

    I’ve been in chronic pain for 12–13 years due to a car crash.
    Expe­ri­ence almost con­stant neck and upper back pain. The catch is I’m deeply involved in a 12 step pro­gram. Been down the opi­ate road and ruined that for myself as a way of legit­i­mate pain relief. I’m work­ing with a decent DC now, but what she can do for me is usu­ally tem­po­rary. Be strong as pos­si­ble all!

  5. Mike - April 13, 2011

    I find the atti­tude of soci­ety becom­ing more extreme because of the inter­net. These days if the per­ceived major­ity don’t agree with some­thing it’s wrong and you are branded an out­cast. When some­thing works for some­one (e.g. opi­ates) it works and if it makes them pro­duc­tive in soci­ety that can only be a good thing. We all need to become less stereo­typ­i­cal, hyp­o­crit­i­cal and more tolerant.

  6. Jude Walter - July 8, 2011

    (Whis­per) “Stud­ies like these are very use­ful and impor­tant to the med­ical indus­try. Results of these stud­ies con­tribute a lot towards the improve­ment of the indus­try. I can relate to the first study which is about the use of opi­oids since I did a paper once about it. But I focused more on its dis­ad­van­tages like they can­not elim­i­nate pain.

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